General NutraceuticalTechnology, LLCContact

Research & products

Botanical medicine research pipeline

GNT combines natural product discovery, immunology, advanced delivery systems, and translational development to address allergic and inflammatory diseases.

01

Food allergy

GNT investigates interventions intended to address persistent pathological IgE and reduce allergic symptoms.

  • IgE-inhibiting natural compounds
  • Nanomedicine for improved compound delivery
  • Fermented foods and probiotic dietary supplements
02

Allergic asthma

The pipeline includes multicomponent botanical approaches and purified natural compounds for allergic and treatment-resistant asthma.

  • ASHMI Phase I and IIa clinical research
  • Eosinophilic and corticosteroid-resistant models
  • Airway-smooth-muscle and eotaxin research
03

Eczema

GNT's proprietary Shi Zhen formulations are being developed for inflammatory skin disease and associated immune dysregulation.

  • Skin-lesion outcomes
  • Peripheral eosinophils
  • Serum IgE
04

Metabolic health

The research portfolio also includes a traditional Chinese medicine-based weight-management formulation, W-LHGT.

  • Botanical formulation
  • Chronic-disease context
  • Translational product development

Botanical & molecular origins

Sources and structures behind the pipeline

A berberine-containing botanical and a prominent molecular view of xanthopurpurin, two natural-product starting points represented in GNT’s research.

European barberry branch with red berries beside an illustrative dish of yellow berberine hydrochloride crystalsScientific visualization

Berberis vulgaris · Berberine HCl

Berberine-containing botanicals

European barberry is a representative berberine-containing plant, shown with an illustrative preparation of the yellow hydrochloride salt used in analytical and formulation work.

Bond-line structure of xanthopurpurin, also known as 1,3-dihydroxyanthraquinonePubChem CID 196978

1,3-Dihydroxyanthraquinone

Xanthopurpurin (XPP)

The bond-line structure takes center stage for this small molecule, whose analog development is represented in GNT’s NIH-supported translational research portfolio.

Intellectual property

Patents associated with GNT team members

Protected discoveries across botanical therapeutics, natural compounds, delivery systems, and immune regulation.

  1. US7820175B2Herbal therapy for the treatment of food allergy
  2. US10406191B2Sophora flavescens compounds that inhibit airway contraction
  3. US10028985B2Traditional Chinese medicine-based weight-loss formulations
  4. US10500169B2Suppression of IgE production by TCM-derived compounds
  5. US11351157B2Treatment of immunological disease using berberine nanoparticles